South Korea’s National Institute of Environmental Research (NIER) issued NIER Announcement No.2016-18 on 30 Sep 2016, making public the results of hazard evaluation of 178 new substances (given number as 2016-418~2016-595) registered under K-REACH. In addition, the hazard properties and classification details of one new substance previously published as No.2016-414 was supplemented.