On January 15, 2020, Taiwan Environment Protection Administration (EPA) released the revised Permit Registration and Approval Regulations for Toxic and Concerned Chemical Substances [1], the name of which, before modification, was Permit Registration and Approval Regulations for Toxic Chemical Substances [2]. From the name, it can be seen that the revised regulations have included the management for the permission, registration, and approval of concerned chemical substances. Besides, the management for the approval of Class 4 toxic chemical substances has also been included in the revised Regulations. Therefore, the Approval Regulations for Class 4 Toxic Chemical Substances were repealed on the same day. The revision and repeal entered into effect simultaneously.